RenalDB: A Knowledge Database for Kidney RNA Expression
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Accession: UG_GRCh38-5PKP1ZoF5BmUSKdF-Q9wA
Description:secreted frizzled-related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776]
Name(s) SFRP1, FRP, FRP-1, SARP2
Other IDs:
Tax IDPositionStrandBiotype(s)
9606 8:41261958-41309497 - protein_coding
Expressed in:
  Adipose, Adrenal, Bladder, Brain, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HEK-293F Cells, HEK-293T Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Muscle, Nephron Progenitor Cells, Nephrons, Ovary, Placenta, Proximal Tubule, Testis
Enriched in:
  Bladder, Breast, Colon, Epithelial Cells, Heart, Kidney, Kidney Cortex, Kidney Tubules, Ovary, Placenta, Testis
Specific to:
  None
Parents
None
Children
Accession Name Sequence Type Position Assembly
UT_GRCh385tYIxCInhSSl9VgYXgdCkg SFRP1-003 transcript 8:41261964-41306990 (-) GRCh38
UT_GRCh38RCWGu3e86VYKi0uN_oEb3g SFRP1-001 transcript 8:41261958-41309497 (-) GRCh38

Expression Patterns




Heat Map
Numeric Values
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Gene Ontology
GO ID Domain Evidence Type GO Description
GO:0001649 biological_process IEP osteoblast differentiation
GO:0001657 biological_process IEA ureteric bud development
GO:0001756 biological_process IEA somitogenesis
GO:0001843 biological_process IEA neural tube closure
GO:0001954 biological_process ISS positive regulation of cell-matr
GO:0002244 biological_process IDA hematopoietic progenitor cell di
GO:0004197 molecular_function IMP cysteine-type endopeptidase acti
GO:0005109 molecular_function IPI frizzled binding
GO:0005515 molecular_function IEA protein binding
GO:0005515 molecular_function IPI protein binding
GO:0005576 cellular_component IEA extracellular region
GO:0005576 cellular_component TAS extracellular region
GO:0005578 cellular_component IDA proteinaceous extracellular matr
GO:0005615 cellular_component IDA extracellular space
GO:0005622 cellular_component IDA intracellular
GO:0005829 cellular_component IDA cytosol
GO:0005886 cellular_component ISS plasma membrane
GO:0006508 biological_process IMP proteolysis
GO:0008144 molecular_function IDA drug binding
GO:0008201 molecular_function IDA heparin binding
GO:0008284 biological_process IDA positive regulation of cell prol
GO:0008285 biological_process IDA negative regulation of cell prol
GO:0008584 biological_process IEA male gonad development
GO:0008585 biological_process IEA female gonad development
GO:0009267 biological_process IEP cellular response to starvation
GO:0009950 biological_process IDA dorsal/ventral axis specificatio
GO:0009952 biological_process IEA anterior/posterior pattern speci
GO:0009986 cellular_component IDA cell surface
GO:0010564 biological_process IMP regulation of cell cycle process
GO:0010629 biological_process IDA negative regulation of gene expr
GO:0010719 biological_process IDA negative regulation of epithelia
GO:0014034 biological_process IEA neural crest cell fate commitmen
GO:0014070 biological_process IDA response to organic cyclic compo
GO:0017147 molecular_function IPI Wnt-protein binding
GO:0021915 biological_process IEA neural tube development
GO:0022601 biological_process IEP menstrual cycle phase
GO:0030097 biological_process IEA hemopoiesis
GO:0030177 biological_process IDA positive regulation of Wnt signa
GO:0030178 biological_process IDA negative regulation of Wnt signa
GO:0030178 biological_process IMP negative regulation of Wnt signa
GO:0030278 biological_process IEA regulation of ossification
GO:0030279 biological_process IDA negative regulation of ossificat
GO:0030279 biological_process IMP negative regulation of ossificat
GO:0030307 biological_process IDA positive regulation of cell grow
GO:0030308 biological_process IDA negative regulation of cell grow
GO:0030336 biological_process IDA negative regulation of cell migr
GO:0030514 biological_process IEA negative regulation of BMP signa
GO:0031012 cellular_component IDA extracellular matrix
GO:0033689 biological_process IMP negative regulation of osteoblas
GO:0035019 biological_process IEA somatic stem cell population mai
GO:0035567 biological_process IBA non-canonical Wnt signaling path
GO:0042493 biological_process IDA response to drug
GO:0042802 molecular_function IPI identical protein binding
GO:0043065 biological_process IDA positive regulation of apoptotic
GO:0043065 biological_process IMP positive regulation of apoptotic
GO:0043066 biological_process IMP negative regulation of apoptotic
GO:0043508 biological_process IEA negative regulation of JUN kinas
GO:0043547 biological_process ISS positive regulation of GTPase ac
GO:0044344 biological_process IDA cellular response to fibroblast
GO:0044345 biological_process IEA stromal-epithelial cell signalin
GO:0045578 biological_process IMP negative regulation of B cell di
GO:0045600 biological_process IDA positive regulation of fat cell
GO:0045668 biological_process IEA negative regulation of osteoblas
GO:0045671 biological_process IEA negative regulation of osteoclas
GO:0045765 biological_process ISS regulation of angiogenesis
GO:0045880 biological_process IMP positive regulation of smoothene
GO:0045892 biological_process IDA negative regulation of transcrip
GO:0045892 biological_process IMP negative regulation of transcrip
GO:0045893 biological_process IDA positive regulation of transcrip
GO:0045893 biological_process IMP positive regulation of transcrip
GO:0046546 biological_process IEA development of primary male sexu
GO:0046676 biological_process IDA negative regulation of insulin s
GO:0046851 biological_process IMP negative regulation of bone remo
GO:0048147 biological_process IDA negative regulation of fibroblas
GO:0048546 biological_process IEA digestive tract morphogenesis
GO:0050679 biological_process IMP positive regulation of epithelia
GO:0050680 biological_process IDA negative regulation of epithelia
GO:0050732 biological_process IDA negative regulation of peptidyl-
GO:0051496 biological_process ISS positive regulation of stress fi
GO:0051894 biological_process ISS positive regulation of focal adh
GO:0060070 biological_process IDA canonical Wnt signaling pathway
GO:0060071 biological_process IEA Wnt signaling pathway, planar ce
GO:0060218 biological_process IDA hematopoietic stem cell differen
GO:0060346 biological_process IEA bone trabecula formation
GO:0060527 biological_process IEA prostate epithelial cord arboriz
GO:0060687 biological_process IEA regulation of branching involved
GO:0060766 biological_process IDA negative regulation of androgen
GO:0070062 cellular_component IDA extracellular exosome
GO:0071305 biological_process IEP cellular response to vitamin D
GO:0071347 biological_process IEP cellular response to interleukin
GO:0071356 biological_process IDA cellular response to tumor necro
GO:0071363 biological_process IDA cellular response to growth fact
GO:0071380 biological_process IEA cellular response to prostagland
GO:0071380 biological_process IEP cellular response to prostagland
GO:0071391 biological_process IDA cellular response to estrogen st
GO:0071392 biological_process IEP cellular response to estradiol s
GO:0071456 biological_process IEP cellular response to hypoxia
GO:0071481 biological_process IEA cellular response to X-ray
GO:0071504 biological_process IDA cellular response to heparin
GO:0071560 biological_process IEP cellular response to transformin
GO:0071773 biological_process IEP cellular response to BMP stimulu
GO:0090090 biological_process IDA negative regulation of canonical
GO:0090090 biological_process IMP negative regulation of canonical
GO:0090090 biological_process TAS negative regulation of canonical
GO:0090175 biological_process IEA regulation of establishment of p
GO:0090179 biological_process IEA planar cell polarity pathway inv
GO:0090244 biological_process IEA Wnt signaling pathway involved i
GO:0090246 biological_process IEA convergent extension involved in
GO:0090263 biological_process IDA positive regulation of canonical
GO:1902043 biological_process IDA positive regulation of extrinsic
GO:2000041 biological_process IEA negative regulation of planar ce
GO:2000052 biological_process IDA positive regulation of non-canon
GO:2000054 biological_process IDA negative regulation of Wnt signa
GO:2000080 biological_process IDA negative regulation of canonical
GO:2000270 biological_process IDA negative regulation of fibroblas
GO:2000271 biological_process IDA positive regulation of fibroblas
GO:2001238 biological_process IEA positive regulation of extrinsic

Homologs
Accession Description Species Homolog Type
UG_GRCm38-csNFeUPbJ0tQMS6mr-qzg Sfrp1 10090 ortholog_one2one
UG_GRCz10e7_n1gVySgPMyquXDL6pgQ sfrp1a 7955 ortholog_one2many
UG_GRCz10pW5v5ia191cSIATwf5Hb4A sfrp1b 7955 ortholog_one2many

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