RenalDB: A Knowledge Database for Kidney RNA Expression
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Accession: UG_GRCh38-6zawOGd--iI5QIadjS2uQ
Description:DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:2976]
Name(s) DNMT1, CXXC9, DNMT, MCMT
Other IDs:
Tax IDPositionStrandBiotype(s)
9606 19:10133345-10231286 - protein_coding
Expressed in:
  Adipose, Adrenal, Bladder, Brain, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HEK-293F Cells, HEK-293T Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Muscle, Nephron Progenitor Cells, Nephrons, Ovary, Placenta, Proximal Tubule, Testis
Enriched in:
  Epithelial Cells, HEK-293 Cells, HEK-293F Cells, HEK-293T Cells, HK-2 Cells, Nephron Progenitor Cells, Ovary, Placenta, Testis
Specific to:
  None
Parents
None
Children
Accession Name Sequence Type Position Assembly
UT_GRCh383HToux6TGdvzATKfTS0ISA DNMT1-029 transcript 19:10140030-10143901 (-) GRCh38
UT_GRCh38aFPQLuUfOyTXR-tHz_XQww DNMT1-201 transcript 19:10133347-10195135 (-) GRCh38
UT_GRCh38Bi03VRcDVXGi9d-kv-7Iug DNMT1-028 transcript 19:10133351-10135517 (-) GRCh38
UT_GRCh38bZW8Zytex1ehJ20AJoda5Q DNMT1-009 transcript 19:10175540-10201192 (-) GRCh38
UT_GRCh38D9xoJo95dpu5Jn_HXHVWIQ DNMT1-021 transcript 19:10140280-10142896 (-) GRCh38
UT_GRCh38Dv0L552eDXVj9nsbJCMvow DNMT1-001 transcript 19:10133346-10195135 (-) GRCh38
UT_GRCh38F55kq46MAD57IUIq8IoUlg DNMT1-018 transcript 19:10154664-10160263 (-) GRCh38
UT_GRCh38FhLtDdlcwSvZEUGrh41Eew DNMT1-002 transcript 19:10133540-10195079 (-) GRCh38
UT_GRCh38hFTMlMSfXHf_MLoP_n9jNA DNMT1-022 transcript 19:10141697-10143791 (-) GRCh38
UT_GRCh38iMGMKJpwadHlRfAxGzLE1g DNMT1-007 transcript 19:10159944-10166666 (-) GRCh38
UT_GRCh38lxkwwoA3VltMqRP1YReyFA DNMT1-027 transcript 19:10137467-10138470 (-) GRCh38
UT_GRCh38L_BfD1gbYyv2xtnMLtW6wQ DNMT1-004 transcript 19:10133345-10144754 (-) GRCh38
UT_GRCh38mJfU1wjnHYyIBVPi1JtVGg DNMT1-024 transcript 19:10140254-10141572 (-) GRCh38
UT_GRCh38NpSsPGZYpTWLaiYxUMYkAw DNMT1-014 transcript 19:10180463-10184559 (-) GRCh38
UT_GRCh38OXoyd02OVrPU99oo_lRhgg DNMT1-010 transcript 19:10180355-10201197 (-) GRCh38
UT_GRCh38PR73cTGof6zZd-YzXb6lsQ DNMT1-026 transcript 19:10137888-10140195 (-) GRCh38
UT_GRCh38s6Q3mt3r-CSDzGZ6HiQxeQ DNMT1-020 transcript 19:10148925-10151697 (-) GRCh38
UT_GRCh38SIyTRGtTpZPcjIE13Bpetg DNMT1-017 transcript 19:10160207-10162983 (-) GRCh38
UT_GRCh38Smk2hdyT6oAw98v-ZF9s8w DNMT1-015 transcript 19:10168330-10194904 (-) GRCh38
UT_GRCh38Tr4zTPPWr5Fm-_44pXqNJA DNMT1-013 transcript 19:10175563-10194626 (-) GRCh38
UT_GRCh38TX73w335frq7c2YM3I5vSg DNMT1-012 transcript 19:10173090-10231286 (-) GRCh38
UT_GRCh38UWr1r9jqN9T7OaI91MaXOw DNMT1-011 transcript 19:10175542-10231273 (-) GRCh38
UT_GRCh38V6YfU02FIE0XZzTIL-APUA DNMT1-016 transcript 19:10159912-10166671 (-) GRCh38
UT_GRCh38wpDjKLSk7D9tMSZt8eWLXw DNMT1-008 transcript 19:10133367-10140130 (-) GRCh38
UT_GRCh38wtbkR9fS1DI0wM_aOdq7sQ DNMT1-025 transcript 19:10140689-10141446 (-) GRCh38
UT_GRCh38x01tIuKNon4i81sJ1gYJkQ DNMT1-023 transcript 19:10140529-10142074 (-) GRCh38
UT_GRCh38xFZxws3SL3wH_yPfKR1GGg DNMT1-006 transcript 19:10133346-10194934 (-) GRCh38
UT_GRCh38ZuHKZ-qYuaB_l66lWkBYPQ DNMT1-019 transcript 19:10149948-10154977 (-) GRCh38
UT_GRCh38_I-FNUfD5wgkVArYOxsa0w DNMT1-005 transcript 19:10177319-10180381 (-) GRCh38

Expression Patterns




Heat Map
Numeric Values
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Gene Ontology
GO ID Domain Evidence Type GO Description
GO:0000122 biological_process IEA negative regulation of transcrip
GO:0000792 cellular_component IEA heterochromatin
GO:0003677 molecular_function IDA DNA binding
GO:0003677 molecular_function IEA DNA binding
GO:0003682 molecular_function IEA chromatin binding
GO:0003690 molecular_function IEA double-stranded DNA binding
GO:0003723 molecular_function IEA RNA binding
GO:0003886 molecular_function IDA DNA (cytosine-5-)-methyltransfer
GO:0003886 molecular_function IEA DNA (cytosine-5-)-methyltransfer
GO:0005515 molecular_function IEA protein binding
GO:0005515 molecular_function IPI protein binding
GO:0005634 cellular_component IDA nucleus
GO:0005634 cellular_component IEA nucleus
GO:0005654 cellular_component TAS nucleoplasm
GO:0005657 cellular_component IEA replication fork
GO:0005721 cellular_component IEA pericentric heterochromatin
GO:0005737 cellular_component IEA cytoplasm
GO:0006306 biological_process IEA DNA methylation
GO:0006306 biological_process TAS DNA methylation
GO:0006351 biological_process IEA transcription, DNA-templated
GO:0007420 biological_process IEA brain development
GO:0007568 biological_process IEA aging
GO:0008134 molecular_function IEA transcription factor binding
GO:0008168 molecular_function IEA methyltransferase activity
GO:0008270 molecular_function IEA zinc ion binding
GO:0008327 molecular_function IEA methyl-CpG binding
GO:0009008 molecular_function IDA DNA-methyltransferase activity
GO:0009008 molecular_function TAS DNA-methyltransferase activity
GO:0009408 biological_process IEA response to heat
GO:0009636 biological_process IEA response to toxic substance
GO:0010033 biological_process IEA response to organic substance
GO:0010212 biological_process IEA response to ionizing radiation
GO:0010216 biological_process IDA maintenance of DNA methylation
GO:0010216 biological_process IEA maintenance of DNA methylation
GO:0010288 biological_process IEA response to lead ion
GO:0010424 biological_process IEA DNA methylation on cytosine with
GO:0010467 biological_process TAS gene expression
GO:0010468 biological_process IEA regulation of gene expression
GO:0010628 biological_process IMP positive regulation of gene expr
GO:0014823 biological_process IEA response to activity
GO:0016458 biological_process IEA gene silencing
GO:0016568 biological_process IEA chromatin modification
GO:0019904 molecular_function IEA protein domain specific binding
GO:0030182 biological_process IEA neuron differentiation
GO:0030331 molecular_function IEA estrogen receptor binding
GO:0031000 biological_process IEA response to caffeine
GO:0031667 biological_process IEA response to nutrient levels
GO:0032259 biological_process IEA methylation
GO:0032355 biological_process IEA response to estradiol
GO:0032496 biological_process IEA response to lipopolysaccharide
GO:0032776 biological_process IEA DNA methylation on cytosine
GO:0032776 biological_process TAS DNA methylation on cytosine
GO:0033189 biological_process IEA response to vitamin A
GO:0033574 biological_process IEA response to testosterone
GO:0036120 biological_process IEA cellular response to platelet-de
GO:0036276 biological_process IEA response to antidepressant
GO:0040029 biological_process TAS regulation of gene expression, e
GO:0042127 biological_process IEA regulation of cell proliferation
GO:0042493 biological_process IEA response to drug
GO:0042826 molecular_function IEA histone deacetylase binding
GO:0043025 cellular_component IEA neuronal cell body
GO:0043234 cellular_component IEA protein complex
GO:0044026 biological_process IEA DNA hypermethylation
GO:0045322 molecular_function IEA unmethylated CpG binding
GO:0045471 biological_process IEA response to ethanol
GO:0045814 biological_process TAS negative regulation of gene expr
GO:0045892 biological_process IEA negative regulation of transcrip
GO:0046498 biological_process IEA S-adenosylhomocysteine metabolic
GO:0046499 biological_process IEA S-adenosylmethioninamine metabol
GO:0046500 biological_process IEA S-adenosylmethionine metabolic p
GO:0051571 biological_process IMP positive regulation of histone H
GO:0051573 biological_process IMP negative regulation of histone H
GO:0051718 molecular_function IEA DNA (cytosine-5-)-methyltransfer
GO:0071230 biological_process IEA cellular response to amino acid
GO:0071284 biological_process IEA cellular response to lead ion
GO:0071560 biological_process IEA cellular response to transformin
GO:0090116 biological_process IEA C-5 methylation of cytosine
GO:1990090 biological_process IEA cellular response to nerve growt

Homologs
Accession Description Species Homolog Type
UG_GRCm38nKLWayU2B5mRN_3apDKpHQ Dnmt1 10090 ortholog_one2one
UG_GRCz10hu0mtC-3a08BgYLjn-M3kg dnmt1 7955 ortholog_one2one

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