RenalDB: A Knowledge Database for Kidney RNA Expression
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Accession: UG_GRCh38-DmWGbwBoM7W-fboeA93Pw
Description:CD274 molecule [Source:HGNC Symbol;Acc:HGNC:17635]
Name(s) CD274, B7-H, B7-H1, B7H1, bA574F11.1, PD-L1, PDCD1LG1, PDL1
Other IDs:
Tax IDPositionStrandBiotype(s)
9606 9:5450503-5470566 + protein_coding
Expressed in:
  Adipose, Adrenal, Bladder, Brain, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HEK-293F Cells, HEK-293T Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Muscle, Nephron Progenitor Cells, Nephrons, Ovary, Placenta, Proximal Tubule, Testis
Enriched in:
  Epithelial Cells, Heart, Kidney, Kidney Cortex, Lung, Muscle, Placenta
Specific to:
  None
Parents
None
Children
Accession Name Sequence Type Position Assembly
UT_GRCh383Evv6abDB57UtYzyvGQiGA CD274-004 transcript 9:5456114-5467866 (+) GRCh38
UT_GRCh389DKEgFBomqwK9_Q4gCGIPQ CD274-002 transcript 9:5462935-5465912 (+) GRCh38
UT_GRCh389ZNydNn4P7DJNufAYaT6mQ CD274-001 transcript 9:5450525-5470547 (+) GRCh38
UT_GRCh38gb-i9vMf3wpxTJ_Lv_B3DQ CD274-201 transcript 9:5450503-5470566 (+) GRCh38
UT_GRCh38oPAy5FW7NQNR4t1kUHIDww CD274-003 transcript 9:5457384-5463238 (+) GRCh38

Expression Patterns




Heat Map
Numeric Values
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Gene Ontology
GO ID Domain Evidence Type GO Description
GO:0005515 molecular_function IEA protein binding
GO:0005515 molecular_function IPI protein binding
GO:0005886 cellular_component TAS plasma membrane
GO:0006955 biological_process IDA immune response
GO:0007165 biological_process IDA signal transduction
GO:0007166 biological_process IDA cell surface receptor signaling
GO:0009897 cellular_component IEA external side of plasma membrane
GO:0009986 cellular_component IEA cell surface
GO:0012505 cellular_component IEA endomembrane system
GO:0016021 cellular_component IEA integral component of membrane
GO:0030335 biological_process IEA positive regulation of cell migr
GO:0031295 biological_process IDA T cell costimulation
GO:0031295 biological_process TAS T cell costimulation
GO:0032689 biological_process IMP negative regulation of interfero
GO:0032693 biological_process IMP negative regulation of interleuk
GO:0034097 biological_process IDA response to cytokine
GO:0042102 biological_process IEA positive regulation of T cell pr
GO:0042102 biological_process TAS positive regulation of T cell pr
GO:0042130 biological_process IEA negative regulation of T cell pr
GO:0046007 biological_process IMP negative regulation of activated
GO:0070062 cellular_component IDA extracellular exosome
GO:1901998 biological_process IEA toxin transport
GO:1903556 biological_process IMP negative regulation of tumor nec
GO:2001181 biological_process IDA positive regulation of interleuk

Homologs
Accession Description Species Homolog Type
UG_GRCm38hNPb9tzGawXNqFweuTjpmw Cd274 10090 ortholog_one2one
UG_GRCz107gHZVGrkbl-5EQDg3_EUMg CD274 7955 ortholog_one2many

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