| Accession: |
UG_GRCh38K2o4RsIecC6Dr6VnGXl2Uw
|
||
|---|---|---|---|
| Description: | programmed cell death 1 ligand 2 [Source:HGNC Symbol;Acc:HGNC:18731] | ||
| Name(s) | PDCD1LG2, B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2 | ||
| Other IDs: | |||
| Tax ID | Position | Strand | Biotype(s) |
| 9606 |
9:5510570-5571254
|
+ | protein_coding |
Expressed in: Adipose, Adrenal, Bladder, Brain, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HEK-293T Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Muscle, Nephron Progenitor Cells, Nephrons, Ovary, Placenta, Proximal Tubule, Testis Enriched in: Adipose, Adrenal, Breast, Colon, Epithelial Cells, Heart, HK-2 Cells, Kidney, Kidney Cortex, Liver, Lung, Muscle, Placenta Specific to: None |
| Parents | |||
|---|---|---|---|
| None |
| Children | ||||
|---|---|---|---|---|
| Accession | Name | Sequence Type | Position | Assembly |
| UT_GRCh385X4_2uhQX2XeAknFSLomRw | PDCD1LG2-001 | transcript | 9:5510570-5571254 (+) | GRCh38 |
Expression Patterns
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|
Gene Ontology |
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|---|---|---|---|
| GO ID | Domain | Evidence Type | GO Description |
| GO:0003674 | molecular_function | ND | molecular_function |
| GO:0005515 | molecular_function | IEA | protein binding |
| GO:0005886 | cellular_component | TAS | plasma membrane |
| GO:0006955 | biological_process | NAS | immune response |
| GO:0012505 | cellular_component | IEA | endomembrane system |
| GO:0016021 | cellular_component | IEA | integral component of membrane |
| GO:0031295 | biological_process | TAS | T cell costimulation |
| GO:0032689 | biological_process | IMP | negative regulation of interfero |
| GO:0032693 | biological_process | IMP | negative regulation of interleuk |
| GO:0042102 | biological_process | IEA | positive regulation of T cell pr |
| GO:0042130 | biological_process | IEA | negative regulation of T cell pr |
| GO:0046007 | biological_process | IMP | negative regulation of activated |
| GO:0070062 | cellular_component | IDA | extracellular exosome |
Homologs |
|||||
| Accession | Description | Species | Homolog Type | ||
| UG_GRCm387Bc_Fyg5_7-3tt9c7YSOQw | Pdcd1lg2 | 10090 | ortholog_one2one | ||
| UG_GRCz107gHZVGrkbl-5EQDg3_EUMg | CD274 | 7955 | ortholog_one2many | ||