RenalDB: A Knowledge Database for Kidney RNA Expression
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Accession: UG_GRCh38Shxer_95rFuItsW6PjuQsA
Description:tumor necrosis factor receptor superfamily, member 10a [Source:HGNC Symbol;Acc:HGNC:11904]
Name(s) TNFRSF10A, Apo2, CD261, DR4, TRAILR-1
Other IDs:
Tax IDPositionStrandBiotype(s)
9606 8:23190452-23225126 - protein_coding
Expressed in:
  Adipose, Adrenal, Bladder, Brain, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HEK-293F Cells, HEK-293T Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Muscle, Nephron Progenitor Cells, Nephrons, Ovary, Placenta, Proximal Tubule, Testis
Enriched in:
  Adipose, Adrenal, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Ovary, Placenta
Specific to:
  None
Parents
None
Children
Accession Name Sequence Type Position Assembly
UT_GRCh381kMNcjxClf958g8ZltEgjg TNFRSF10A-003 transcript 8:23191814-23197273 (-) GRCh38
UT_GRCh38dO5x5vycq7arURpL9OGAHA TNFRSF10A-001 transcript 8:23190452-23225126 (-) GRCh38
UT_GRCh38luh7bykNr80O0zWL2-iflw TNFRSF10A-201 transcript 8:23191649-23225061 (-) GRCh38
UT_GRCh38NucNSgk8WsWlwGpUlsv-Bg TNFRSF10A-002 transcript 8:23199886-23224600 (-) GRCh38

Expression Patterns




Heat Map
Numeric Values
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Gene Ontology
GO ID Domain Evidence Type GO Description
GO:0002020 molecular_function IPI protease binding
GO:0004872 molecular_function NAS receptor activity
GO:0005031 molecular_function IBA tumor necrosis factor-activated
GO:0005035 molecular_function TAS death receptor activity
GO:0005515 molecular_function IEA protein binding
GO:0005515 molecular_function IPI protein binding
GO:0005622 cellular_component NAS intracellular
GO:0005886 cellular_component TAS plasma membrane
GO:0005887 cellular_component IBA integral component of plasma mem
GO:0006915 biological_process NAS apoptotic process
GO:0006915 biological_process TAS apoptotic process
GO:0006919 biological_process TAS activation of cysteine-type endo
GO:0006954 biological_process IBA inflammatory response
GO:0006955 biological_process IBA immune response
GO:0007165 biological_process IEA signal transduction
GO:0007165 biological_process TAS signal transduction
GO:0007166 biological_process TAS cell surface receptor signaling
GO:0007250 biological_process NAS activation of NF-kappaB-inducing
GO:0007275 biological_process IBA multicellular organismal develop
GO:0008134 molecular_function IPI transcription factor binding
GO:0008625 biological_process NAS extrinsic apoptotic signaling pa
GO:0009986 cellular_component IDA cell surface
GO:0010939 biological_process TAS regulation of necrotic cell deat
GO:0012501 biological_process TAS programmed cell death
GO:0016021 cellular_component IC integral component of membrane
GO:0016021 cellular_component IEA integral component of membrane
GO:0032496 biological_process IBA response to lipopolysaccharide
GO:0033209 biological_process IBA tumor necrosis factor-mediated s
GO:0036462 biological_process IDA TRAIL-activated apoptotic signal
GO:0042127 biological_process IBA regulation of cell proliferation
GO:0043154 biological_process TAS negative regulation of cysteine-
GO:0045569 molecular_function IEA TRAIL binding
GO:0045569 molecular_function NAS TRAIL binding
GO:0070266 biological_process TAS necroptotic process
GO:0071260 biological_process IEP cellular response to mechanical
GO:0097191 biological_process IDA extrinsic apoptotic signaling pa
GO:0097191 biological_process TAS extrinsic apoptotic signaling pa
GO:0097296 biological_process TAS activation of cysteine-type endo
GO:0097300 biological_process TAS programmed necrotic cell death
GO:1902041 biological_process TAS regulation of extrinsic apoptoti

Homologs
Accession Description Species Homolog Type
UG_GRCm38C3WrFosYCmTgwMwOU1y26g Tnfrsf10b 10090 ortholog_one2many
UG_GRCz104gbaqkBGNE8lEwafDDDwdA tnfrsfa 7955 ortholog_many2many
UG_GRCz105znPlPEQwavWDon6Hbi9_Q hdr 7955 ortholog_many2many

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