RenalDB: A Knowledge Database for Kidney RNA Expression
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Accession: UG_GRCh38izyVJ-k2QZhbD68qZMzacw
Description:UDP glucuronosyltransferase 1 family, polypeptide A1 [Source:HGNC Symbol;Acc:HGNC:12530]
Name(s) UGT1A1, GNT1, UGT1, UGT1A
Other IDs:
Tax IDPositionStrandBiotype(s)
9606 2:233760248-233773299 + protein_coding
Expressed in:
  Bladder, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HEK-293T Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Nephrons, Ovary, Proximal Tubule, Testis
Enriched in:
  Bladder, Kidney, Kidney Cortex, Liver
Specific to:
  None
Parents
None
Children
Accession Name Sequence Type Position Assembly
UT_GRCh385GnFLkk5vZt-3oZoEmLLRA UGT1A1-001 transcript 2:233760248-233773299 (+) GRCh38
UT_GRCh38Ir6sKreo230DEqaf8IvwwA UGT1A1-002 transcript 2:233760288-233771615 (+) GRCh38

Expression Patterns




Heat Map
Numeric Values
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Gene Ontology
GO ID Domain Evidence Type GO Description
GO:0001889 biological_process IEA liver development
GO:0001972 molecular_function IDA retinoic acid binding
GO:0004857 molecular_function IDA enzyme inhibitor activity
GO:0005496 molecular_function IDA steroid binding
GO:0005783 cellular_component IDA endoplasmic reticulum
GO:0005783 cellular_component IEA endoplasmic reticulum
GO:0005783 cellular_component NAS endoplasmic reticulum
GO:0005789 cellular_component NAS endoplasmic reticulum membrane
GO:0005789 cellular_component TAS endoplasmic reticulum membrane
GO:0005887 cellular_component IEA integral component of plasma mem
GO:0006778 biological_process TAS porphyrin-containing compound me
GO:0006789 biological_process TAS bilirubin conjugation
GO:0006805 biological_process TAS xenobiotic metabolic process
GO:0006953 biological_process IEA acute-phase response
GO:0007584 biological_process IEA response to nutrient
GO:0007586 biological_process NAS digestion
GO:0008152 biological_process IEA metabolic process
GO:0008202 biological_process IC steroid metabolic process
GO:0008210 biological_process TAS estrogen metabolic process
GO:0009813 biological_process IBA flavonoid biosynthetic process
GO:0010033 biological_process IEA response to organic substance
GO:0014070 biological_process IEA response to organic cyclic compo
GO:0015020 molecular_function IDA glucuronosyltransferase activity
GO:0015020 molecular_function IEA glucuronosyltransferase activity
GO:0015020 molecular_function ISS glucuronosyltransferase activity
GO:0016758 molecular_function IEA transferase activity, transferri
GO:0017144 biological_process IC drug metabolic process
GO:0019899 molecular_function IEA enzyme binding
GO:0019899 molecular_function IPI enzyme binding
GO:0031100 biological_process IEA organ regeneration
GO:0032496 biological_process IEA response to lipopolysaccharide
GO:0032870 biological_process IBA cellular response to hormone sti
GO:0032870 biological_process IEA cellular response to hormone sti
GO:0034663 cellular_component IEA endoplasmic reticulum chaperone
GO:0042167 biological_process TAS heme catabolic process
GO:0042493 biological_process IEA response to drug
GO:0042573 biological_process IC retinoic acid metabolic process
GO:0042594 biological_process IEA response to starvation
GO:0042803 molecular_function IDA protein homodimerization activit
GO:0043086 biological_process IDA negative regulation of catalytic
GO:0043231 cellular_component IEA intracellular membrane-bounded o
GO:0044281 biological_process TAS small molecule metabolic process
GO:0045471 biological_process IEA response to ethanol
GO:0045922 biological_process ISS negative regulation of fatty aci
GO:0045939 biological_process IC negative regulation of steroid m
GO:0046483 biological_process IC heterocycle metabolic process
GO:0046982 molecular_function IDA protein heterodimerization activ
GO:0046982 molecular_function IPI protein heterodimerization activ
GO:0048545 biological_process IEA response to steroid hormone
GO:0051384 biological_process IEA response to glucocorticoid
GO:0051552 biological_process IDA flavone metabolic process
GO:0052695 biological_process IDA cellular glucuronidation
GO:0052695 biological_process ISS cellular glucuronidation
GO:0052695 biological_process TAS cellular glucuronidation
GO:0052696 biological_process IDA flavonoid glucuronidation
GO:0052697 biological_process IDA xenobiotic glucuronidation
GO:0070069 cellular_component IEA cytochrome complex
GO:0070980 biological_process IEA biphenyl catabolic process
GO:0071361 biological_process IEA cellular response to ethanol
GO:0071385 biological_process IEA cellular response to glucocortic
GO:1904224 biological_process ISS negative regulation of glucurono
GO:2001030 biological_process IDA negative regulation of cellular

Homologs
Accession Description Species Homolog Type
UG_GRCm38WHRsR49eFGcT1EVEhIMttw Ugt1a1 10090 ortholog_one2one
UG_GRCz10BjviJg1g6JCdHILFwuAXsw ugt1b2 7955 ortholog_many2many
UG_GRCz10cEj26S1tgw2aQhv52SIgDw ugt1b4 7955 ortholog_many2many
UG_GRCz10foLltq_sUkcilMZBGGuOIw ugt1b1 7955 ortholog_many2many
UG_GRCz10mhgi4k1_C1R3h8d1Yjr-Ow ugt1b7 7955 ortholog_many2many
UG_GRCz10NVHi85Ehn_2FbRV1Cw1VVA ugt1b5 7955 ortholog_many2many
UG_GRCz10p2rCBry7K2-I0R776lUj0w ugt1b3 7955 ortholog_many2many
UG_GRCz10tzBxfnrdsO8Epw7RdS-ApA ugt1ab 7955 ortholog_many2many

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