RenalDB: A Knowledge Database for Kidney RNA Expression
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Accession: UG_GRCh38-1jKF0m0GdJtOF5cK-yu0Q
Description:H2A histone family, member X [Source:HGNC Symbol;Acc:HGNC:4739]
Name(s) H2AFX, H2AX
Other IDs:
Tax IDPositionStrandBiotype(s)
9606 11:119093854-119095467 - protein_coding
Expressed in:
  Adipose, Adrenal, Bladder, Brain, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HEK-293F Cells, HEK-293T Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Muscle, Nephron Progenitor Cells, Nephrons, Ovary, Placenta, Proximal Tubule, Testis
Enriched in:
  HEK-293 Cells, HEK-293F Cells, HEK-293T Cells, HK-2 Cells, Kidney, Nephron Progenitor Cells, Placenta
Specific to:
  None
Parents
None
Children
Accession Name Sequence Type Position Assembly
UT_GRCh38-1jKF0m0GdJtOF5cK-yu0Q H2AFX-001 transcript 11:119093854-119095467 (-) GRCh38
UT_GRCh38Bn9Lrxt3t7Cl6ORAQxCSeg H2AFX-002 transcript 11:119093879-119095449 (-) GRCh38

Expression Patterns




Heat Map
Numeric Values
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Gene Ontology
GO ID Domain Evidence Type GO Description
GO:0000077 biological_process IDA DNA damage checkpoint
GO:0000724 biological_process IEA double-strand break repair via h
GO:0000724 biological_process TAS double-strand break repair via h
GO:0000781 cellular_component IDA chromosome, telomeric region
GO:0000785 cellular_component IEA chromatin
GO:0000786 cellular_component IEA nucleosome
GO:0000790 cellular_component IBA nuclear chromatin
GO:0000790 cellular_component IEA nuclear chromatin
GO:0000794 cellular_component IEA condensed nuclear chromosome
GO:0001673 cellular_component IEA male germ cell nucleus
GO:0001741 cellular_component IEA XY body
GO:0003677 molecular_function IBA DNA binding
GO:0003677 molecular_function IEA DNA binding
GO:0003677 molecular_function NAS DNA binding
GO:0003684 molecular_function IEA damaged DNA binding
GO:0005515 molecular_function IEA protein binding
GO:0005515 molecular_function IPI protein binding
GO:0005634 cellular_component IDA nucleus
GO:0005634 cellular_component IEA nucleus
GO:0005654 cellular_component TAS nucleoplasm
GO:0005657 cellular_component IEA replication fork
GO:0005694 cellular_component IEA chromosome
GO:0006281 biological_process IEA DNA repair
GO:0006281 biological_process TAS DNA repair
GO:0006302 biological_process NAS double-strand break repair
GO:0006302 biological_process TAS double-strand break repair
GO:0006303 biological_process TAS double-strand break repair via n
GO:0006325 biological_process IBA chromatin organization
GO:0006334 biological_process NAS nucleosome assembly
GO:0006342 biological_process IBA chromatin silencing
GO:0006974 biological_process IDA cellular response to DNA damage
GO:0007283 biological_process IEA spermatogenesis
GO:0010212 biological_process NAS response to ionizing radiation
GO:0016032 biological_process IEA viral process
GO:0019899 molecular_function IPI enzyme binding
GO:0021987 biological_process IEA cerebral cortex development
GO:0035861 cellular_component IDA site of double-strand break
GO:0042393 molecular_function IPI histone binding
GO:0045739 biological_process NAS positive regulation of DNA repai
GO:0046982 molecular_function IEA protein heterodimerization activ
GO:0051321 biological_process IEA meiotic cell cycle
GO:0070062 cellular_component IDA extracellular exosome
GO:0071480 biological_process IEA cellular response to gamma radia
GO:0090398 biological_process IEA cellular senescence

Homologs
Accession Description Species Homolog Type
UG_GRCm38a2nKLNZQSl09DRAjlEADZQ H2afx 10090 ortholog_one2one
UG_GRCz10RBiJpkR4Sta_V9dK_JL1lQ h2afx 7955 ortholog_one2one

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