RenalDB: A Knowledge Database for Kidney RNA Expression
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Accession: UG_GRCh3841UVSxO9H7Gk3qY6ZGnTNA
Description:major histocompatibility complex, class II, DR beta 1 [Source:HGNC Symbol;Acc:HGNC:4948]
Name(s) HLA-DRB1, HLA-DR1B
Other IDs:
Tax IDPositionStrandBiotype(s)
9606 6:32552990-32589848 - protein_coding
Expressed in:
  Adipose, Adrenal, Bladder, Brain, Breast, Colon, Epithelial Cells, Heart, HEK-293 Cells, HEK-293F Cells, HEK-293T Cells, HK-2 Cells, Kidney, Kidney Cortex, Kidney Tubules, Liver, Lung, Muscle, Nephron Progenitor Cells, Nephrons, Ovary, Placenta, Proximal Tubule, Testis
Enriched in:
  Adipose, Adrenal, Breast, Colon, Heart, Kidney, Kidney Cortex, Kidney Tubules, Lung, Ovary, Placenta
Specific to:
  None
Parents
None
Children
Accession Name Sequence Type Position Assembly
UT_GRCh38A1G-lQ-B7ZFE_qJSAS1JfA HLA-DRB1-001 transcript 6:32578769-32589848 (-) GRCh38
UT_GRCh38d7m8Ia39foxJLSI2FISbjA HLA-DRB1-201 transcript 6:32552990-32589805 (-) GRCh38

Expression Patterns




Heat Map
Numeric Values
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Gene Ontology
GO ID Domain Evidence Type GO Description
GO:0000139 cellular_component TAS Golgi membrane
GO:0001618 molecular_function IEA virus receptor activity
GO:0002381 biological_process ISS immunoglobulin production involv
GO:0002437 biological_process ISS inflammatory response to antigen
GO:0002455 biological_process ISS humoral immune response mediated
GO:0002504 biological_process IEA antigen processing and presentat
GO:0002506 biological_process IDA polysaccharide assembly with MHC
GO:0005515 molecular_function IEA protein binding
GO:0005765 cellular_component IDA lysosomal membrane
GO:0005765 cellular_component TAS lysosomal membrane
GO:0005886 cellular_component TAS plasma membrane
GO:0006955 biological_process IEA immune response
GO:0006955 biological_process ISS immune response
GO:0009897 cellular_component ISS external side of plasma membrane
GO:0009986 cellular_component IDA cell surface
GO:0012507 cellular_component TAS ER to Golgi transport vesicle me
GO:0016020 cellular_component IDA membrane
GO:0016020 cellular_component IEA membrane
GO:0016020 cellular_component NAS membrane
GO:0016021 cellular_component IEA integral component of membrane
GO:0016045 biological_process ISS detection of bacterium
GO:0019221 biological_process TAS cytokine-mediated signaling path
GO:0019882 biological_process IEA antigen processing and presentat
GO:0019886 biological_process TAS antigen processing and presentat
GO:0023026 molecular_function IDA MHC class II protein complex bin
GO:0030658 cellular_component TAS transport vesicle membrane
GO:0030666 cellular_component TAS endocytic vesicle membrane
GO:0030669 cellular_component TAS clathrin-coated endocytic vesicl
GO:0031295 biological_process TAS T cell costimulation
GO:0031902 cellular_component IDA late endosome membrane
GO:0032395 molecular_function NAS MHC class II receptor activity
GO:0032588 cellular_component TAS trans-Golgi network membrane
GO:0032673 biological_process ISS regulation of interleukin-4 prod
GO:0032689 biological_process ISS negative regulation of interfero
GO:0035774 biological_process ISS positive regulation of insulin s
GO:0042088 biological_process ISS T-helper 1 type immune response
GO:0042130 biological_process ISS negative regulation of T cell pr
GO:0042605 molecular_function IDA peptide antigen binding
GO:0042605 molecular_function ISS peptide antigen binding
GO:0042613 cellular_component IDA MHC class II protein complex
GO:0042613 cellular_component IEA MHC class II protein complex
GO:0042613 cellular_component ISS MHC class II protein complex
GO:0046718 biological_process IEA viral entry into host cell
GO:0050852 biological_process TAS T cell receptor signaling pathwa
GO:0051262 biological_process ISS protein tetramerization
GO:0060333 biological_process TAS interferon-gamma-mediated signal
GO:0070062 cellular_component IDA extracellular exosome
GO:0071556 cellular_component TAS integral component of lumenal si
GO:2001179 biological_process ISS regulation of interleukin-10 sec

Homologs
Accession Description Species Homolog Type
UG_GRCm38bu1n_W4t9Wi15pAYV7xFAQ H2-Eb1 10090 ortholog_many2many
UG_GRCm38nupZJ9E5QbuToYArhuuE4g H2-Eb2 10090 ortholog_many2many
UG_GRCz102lPS3qhP_Ia9DBm0srK0Ng si:busm1-104n07.3 7955 ortholog_many2many
UG_GRCz106N796CupK03WDk9FB6V2qA si:busm1-228j01.4 7955 ortholog_many2many
UG_GRCz1086hL4il1eVUbFv2c_4m1LA mhc2dbb 7955 ortholog_many2many
UG_GRCz109k9Ck9C3D5rqekcEeaePLw si:busm1-228j01.6 7955 ortholog_many2many
UG_GRCz10BRpv7L48ovJln471ySfhGg zgc:103700 7955 ortholog_many2many
UG_GRCz10c4kTr4kjF8sD0xl6DLqMXQ si:busm1-194e12.12 7955 ortholog_many2many
UG_GRCz10Dd_oreLGUQ6HF8D6a-ipCg wu:fd58b11 7955 ortholog_many2many
UG_GRCz10IZ3tyXoSOv7mVsE_bweQbw mhc2dab 7955 ortholog_many2many
UG_GRCz10UXA9EdGMUhzQfktjRQY1rQ si:dkey-33b17.3 7955 ortholog_many2many
UG_GRCz10wltTzso6YqZ7oUF5AWHH5w si:zfos-2070c2.3 7955 ortholog_many2many

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